Publications

Methodology

Wei Zong, Danyang Li, Marianne L Seney, Colleen A Mcclung, and George C Tseng. (2024) Model-based multifacet clustering with high-dimensional omics applications. Biostatistics. paper

Yujia Li^, Liu Peng^, Wenjia Wang^, Wei Zong, Yusi Fang, Zhao Ren, Lu Tang, Juan Celedon, Steffi Oesterreich, and George C Tseng. (2024) Outcome-guided disease subtyping by generative model and weighted joint likelihood in transcriptomic applications. Annals of Applied Statistics, pages 18:1947–1964. paper

Wei Zong, Tanbin Rahman, Li Zhu, Xiangrui Zeng, Yingjin Zhang, Jian Zou, Song Liu, Zhao Ren, Jingyi Jessica Li, Steffi Osterreich, Tianzhou Ma, George C. Tseng. (2023) Transcriptomic congruence analysis for evaluating model organisms. Proceedings of the National Academy of Sciences. paper

Wei Zong, Marianne L. Seney, Kyle D. Ketchesin, Michael T. Gorczyca, Andrew C. Liu, Karyn A. Esser, George C. Tseng, Colleen A. McClung, Zhiguang Huo. (2023) Experimental design and power calculation in omics circadian rhythmicity detection. Statistics in Medicine. paper

Xiangning Xue, Wei Zong, Zhiguang Huo, Kyle D. Ketchesin, Madeline R. Scott, Kaitlyn A. Petersen, Ryan W. Logan, Marianne L. Seney , Colleen McClung and George Tseng. (2023) DiffCircaPipeline: A framework for multifaceted characterization of differential rhythmicity. Bioinformatics. paper

Xiangrui Zeng^, Wei Zong^, Chien‑Wei Lin, Zhou Fang, Tianzhou Ma, David A Lewis, John F Enwright, George C Tseng. (2020) Comparative Pathway Integrator: a framework of meta‑analytic integration of multiple transcriptomic studies for consensual and differential pathway analysis. Genes. paper

Application

Lauren M. DePoy, Kaitlyn A. Petersen, Wei Zong, Kyle D. Ketchesin, Ross C. Matthaei, RuoFei Yin, Megan S. Perez, Chelsea A. Vadnie, Darius Becker-Krail, Madeline R. Scott, George C Tseng, Colleen A. McClung. (2024) Cell-type and sex-specific rhythmic gene expression in the nucleus accumbens. Molecular Psychiatry. paper

Kaitlyn A Petersen, Wei Zong, Lauren M Depoy, Madeline R Scott, Vaishnavi G Shankar, Jennifer N Burns, Allison J Cerwensky, Sam-Moon Kim, Kyle D Ketchesin, George C Tseng, Colleen A McClung. (2024) Comparative rhythmic transcriptome profiling of human and mouse striatal subregions. Neuropsychopharmacology. paper

Kyle D Ketchesin^, Wei Zong^, Mariah A Hildebrand, Madeline R Scott, Marianne L Seney, Kelly M Cahill, Vaishnavi G Shankar, Jill R Glausier, David A Lewis, George C Tseng, Colleen A McClung. (2023) Diurnal alterations in gene expression across striatal subregions in psychosis. Biological Psychiatry. paper

Madeline R Scott, Wei Zong, Kyle D Ketchesin, Marianne L Seney, George C Tseng, Bokai Zhu, Colleen A McClung. (2023) Twelve-hour rhythms in transcript expression within the human dorsolateral prefrontal cortex are altered in schizophrenia. PLoS Biology. paper

Xiangning Xue, Wei Zong, Jill R Glausier, Sam-Moon Kim, Micah A Shelton, BaDoi N Phan, Chaitanya Srinivasan, Andreas R Pfenning, George C Tseng, David A Lewis, Marianne L Seney, Ryan W. Logan. (2022) Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder. Translational Psychiatry. paper

Darius D Becker‑Krail, Kyle D Ketchesin, Jennifer N Burns, Wei Zong, Mariah A Hildebrand, Lauren M DePoy, Chelsea A Vadnie, George C Tseng, Ryan W Logan, Yanhua H Huang, Colleen A McClung. (2022) Astrocyte molecular clock function in the nucleus accumbens is important for reward‑related behavior. Biological Psychiatry. paper

Kyle D Ketchesin^, Wei Zong^, Mariah A Hildebrand, Marianne L Seney, Kelly M Cahill, Madeline R Scott, Vaishnavi G Shankar, Jill R Glausier, David A Lewis, George C Tseng, Colleen A McClung. (2021) Diurnal rhythms across the human dorsal and ventral striatum. Proceedings of the National Academy of Sciences. paper

Marianne L Seney, Sam-Moon Kim, Jill R Glausier, Mariah A Hildebrand, Xiangning Xue, Wei Zong, Jiebiao Wang, Micah A Shelton, BaDoi N Phan, Chaitanya Srinivasan, Andreas R Pfenning, George C. Tseng, David A Lewis, Zachary Freyberg, Ryan W. Logan. (2021) Transcriptional alterations in dorsolateral prefrontal cortex and nucleus accumbens implicate neuroinflammation and synaptic remodeling in opioid use disorder. Biological psychiatry. paper

Despoina Aslanoglou, Suzanne Bertera, Marta Sánchez‑Soto, R Benjamin Free, Jeongkyung Lee, Wei Zong, Xiangning Xue, Shristi Shrestha, Marcela Brissova, Ryan W Logan, Claes B Wollheim, Massimo Trucco, Vijay K Yechoor, David R Sibley, Rita Bottino, Zachary Freyberg. (2021) Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors. Translational psychiatry. paper

Ryan W Logan, Angela R Ozburn, Rachel N Arey, Kyle D Ketchesin, Alicia Winquist, Andrew Crain, Brian TD Tobe, Darius Becker‑Krail, Matthew B Jarpe, Xiangning Xue, Wei Zong, Zhiguang Huo, Puja K Parekh, Xiyu Zhu, Ethan Fitzgerald, Hui Zhang, Jeffrey Oliver‑Smith, Lauren M DePoy, Mariah A Hildebrand, Evan Y Snyder, George C Tseng, Colleen A McClung. (2021) Valproate reverses mania‑like behaviors in mice via preferential targeting of HDAC2. Molecular psychiatry. paper

Lauren M DePoy, Darius D Becker‑Krail, Wei Zong, Kaitlyn Petersen, Neha M Shah, Jessica H Brandon, Alyssa M Miguelino, George C Tseng, Ryan W Logan, Colleen A McClung. (2021) Circadian‑dependent and sex‑dependent increases in intravenous cocaine self‑administration in Npas2 mutant mice. Journal of Neuroscience. paper

Marianne L Seney, Kelly Cahill, John F Enwright, Ryan W Logan, Zhiguang Huo, Wei Zong, George Tseng, Colleen A McClung. (2019) Diurnal rhythms in gene expression in the prefrontal cortex in schizophrenia. Nature Communications. paper